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  "Description": "Use standard genomics file format (BED) and a table of\northologs to illustrate synteny conservation at the genome-wide\nscale. Significantly conserved linkage groups are identified as\ndescribed in Simakov et al. (2020)\n<doi:10.1038/s41559-020-1156-z> and displayed on an Oxford Grid\n(Edwards (1991) <doi:10.1111/j.1469-1809.1991.tb00394.x>) or a\nchord diagram as in Simakov et al. (2022)\n<doi:10.1126/sciadv.abi5884>. The package provides a function\nthat uses a network-based greedy algorithm to find communities\n(Clauset et al. (2004) <doi:10.1103/PhysRevE.70.066111>) and so\nautomatically order the chromosomes on the plot to improve\ninterpretability.",
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    "get_syntenic_genes",
    "load_orthologs",
    "plot_chord_diagram",
    "plot_macrosynteny",
    "plot_oxford_grid",
    "reorder_macrosynteny",
    "reorder_multiple_macrosyntenies",
    "reverse_species_order",
    "subset_linkage_orthologs"
  ],
  "_help": [
    {
      "page": "compute_linkage_groups",
      "title": "Compute Linkage groups",
      "topics": [
        "compute_linkage_groups"
      ]
    },
    {
      "page": "compute_macrosynteny",
      "title": "Compute significant macrosynteny blocks",
      "topics": [
        "compute_macrosynteny"
      ]
    },
    {
      "page": "get_syntenic_genes",
      "title": "get the syntenic genes as a table",
      "topics": [
        "get_syntenic_genes"
      ]
    },
    {
      "page": "load_orthologs",
      "title": "load orthologs with their genomic coordinates.",
      "topics": [
        "load_orthologs"
      ]
    },
    {
      "page": "plot_chord_diagram",
      "title": "plot the Macro-synteny as a chord diagram",
      "topics": [
        "plot_chord_diagram"
      ]
    },
    {
      "page": "plot_macrosynteny",
      "title": "Plot Macro-synteny",
      "topics": [
        "plot_macrosynteny"
      ]
    },
    {
      "page": "plot_oxford_grid",
      "title": "plot the Macro-synteny as an oxford grid.",
      "topics": [
        "plot_oxford_grid"
      ]
    },
    {
      "page": "reorder_macrosynteny",
      "title": "Reorder the mbh_df before plotting",
      "topics": [
        "reorder_macrosynteny"
      ]
    },
    {
      "page": "reorder_multiple_macrosyntenies",
      "title": "Reorder the chromosomes of two or more species before plotting",
      "topics": [
        "reorder_multiple_macrosyntenies"
      ]
    },
    {
      "page": "reverse_species_order",
      "title": "Reverse order of the species in an orthologs_df.",
      "topics": [
        "reverse_species_order"
      ]
    },
    {
      "page": "subset_linkage_orthologs",
      "title": "Subset Orthologs contained in conserved linkage groups",
      "topics": [
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      "filename": "macrosyntR.html",
      "title": "macrosyntR",
      "author": "Sami El Hilali",
      "engine": "knitr::rmarkdown",
      "headings": [
        "Overview :",
        "Step-by-step tutorial :",
        "1 - Pre-processing :",
        "1.1 - Foreword :",
        "1.2 - Example using two species (rbhXpress) :",
        "1.3 - Example using 3 species (Orthofinder) :",
        "2 - Load the data :",
        "3 - Compute linkage groups :",
        "4 - Reorder chromosome levels to group the linkage groups in clusters :",
        "4.1 - Automatic reordering using a network-based greedy algorithm :",
        "4.2 - Manually reorder/subset the Chromosomes :",
        "5 - Plot directly with reordering the linkage groups and coloring  :",
        "6 - Customize the plots :",
        "6.1 - customize the legend :",
        "6.2 - change the color palette :",
        "7 - Integrate additional information using colors :",
        "8 - plot a chord diagram :"
      ],
      "created": "2022-10-26 20:36:24",
      "modified": "2023-11-06 15:06:56",
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